Llwytho...

Dissecting signaling through activation of specific Src-effector complexes in vivo

We describe an approach to selectively activate a kinase in a specific protein complex or at a specific subcellular location within living cells, and within minutes. This reveals the effects of specific kinase pathways without time for genetic compensation. The new technique, dubbed RapRTAP (rapamyc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Karginov, A.V., Tsygankov, D., Berginski, M., Chu, P.-H., Trudeau, E.D., Yi, J.J., Gomez, S., Elston, T.C., Hahn, K.M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064790/
https://ncbi.nlm.nih.gov/pubmed/24609359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1477
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