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Dissecting signaling through activation of specific Src-effector complexes in vivo
We describe an approach to selectively activate a kinase in a specific protein complex or at a specific subcellular location within living cells, and within minutes. This reveals the effects of specific kinase pathways without time for genetic compensation. The new technique, dubbed RapRTAP (rapamyc...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4064790/ https://ncbi.nlm.nih.gov/pubmed/24609359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1477 |
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