Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats

We generated spinal motoneurons from embryonic stem (ES) cells to determine the developmental potential of these cells in vitro and their capacity to replace motoneurons in the adult mammalian spinal cord. ES cell-derived motoneurons extended long axons, formed neuromuscular junctions, and induced m...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Harper, James M., Krishnan, Chitra, Darman, Jessica S., Deshpande, Deepa M., Peck, Schonze, Shats, Irina, Backovic, Stephanie, Rothstein, Jeffrey D., Kerr, Douglas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC406476/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15118094/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401103101
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