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Regulation of cardiac contractility by Rab4-modulated β2-adrenergic receptor recycling
Catecholaminergic activation of myocardial β-adrenergic receptors (βAR) is the principle mechanism regulating cardiac function. Agonists desensitize βAR through G protein-coupled receptor kinase-mediated uncoupling and β-arrestin-mediated internalization. Although inhibition of myocardial G protein-...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC406469/ https://ncbi.nlm.nih.gov/pubmed/15105445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308335101 |
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