Nalaganje...
Negative selection of semimature CD4(+)8(-)HSA(+) thymocytes requires the BH3-only protein Bim but is independent of death receptor signaling
T cell receptor/CD3 ligation induces apoptosis in semimature CD4(+)8(-)HSA(+) thymocytes, and this helps establish immunological tolerance and constitutes one of the safeguards against autoimmune disease. We analyzed several knockout and transgenic mouse lines and found that T cell receptor/CD3-liga...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC406464/ https://ncbi.nlm.nih.gov/pubmed/15118096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305757101 |
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