Dynamic Interactions Between TIP60 and p300 Regulate FOXP3 Function Through a Structural Switch Defined by a Single Lysine on TIP60

The human FOXP3 molecule is an oligomeric transcriptional factor able to mediate activities that characterize T regulatory cells, a class of lymphocytes central to the regulation of immune responses. The activity of FOXP3 is regulated at the post-translational level, in part by two histone acetyltra...

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Hauptverfasser: Xiao, Yan, Nagai, Yasuhiro, Deng, Guoping, Ohtani, Takuya, Zhu, Zhiqiang, Zhou, Zhaocai, Zhang, Hongtao, Ji, Mei Q, Hancock, Wayne W., Samanta, Arabinda, Lough, John W., Greene, Mark I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064594/
https://ncbi.nlm.nih.gov/pubmed/24835996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.021
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