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Anaphylaxis and mortality induced by treatment of mice with anti-VLA-4 antibody and pertussis toxin

Antibody-mediated blockade of the adhesion molecule very late antigen-4 (VLA-4) has been shown to ameliorate disease in human multiple sclerosis (MS) patients and experimental autoimmune encephalomyelitis (EAE) animal models. We wanted to determine whether anti-VLA-4 antibody treatment affected the...

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Detalhes bibliográficos
Main Authors: Ji, Niannian, Rao, Nagarjun, Guentzel, Neal M., Arulanandam, Bernard P., Forsthuber, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064569/
https://ncbi.nlm.nih.gov/pubmed/21270409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000907
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