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Induction of polyclonal CD8+ T cell activation and effector function by Pertussis toxin
Pertussis toxin (PTX) has pronounced adjuvant activity and strongly enhances innate and adaptive immune responses, including increased antibody production and Th1/Th2 cytokine production. Adjuvant effects of PTX on Th1 and Th2 cells are primarily mediated via CD80/86 costimulation via enhanced expre...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062196/ https://ncbi.nlm.nih.gov/pubmed/21130421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2010.11.003 |
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