Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists

Signal transduction occurs by the reversible assembly of oligomeric protein complexes that include both enzymatic proteins and proteins without known enzymatic activity. These nonenzymatic components can serve as scaffolds or anchors and regulate the efficiency, specificity, and localization of the...

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Bibliografiska uppgifter
Huvudupphovsmän: Vomastek, Tomas, Schaeffer, Hans-Joerg, Tarcsafalvi, Adel, Smolkin, Mark E., Bissonette, Eric A., Weber, Michael J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2004
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC406452/
https://ncbi.nlm.nih.gov/pubmed/15118098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305894101
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