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Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists

Signal transduction occurs by the reversible assembly of oligomeric protein complexes that include both enzymatic proteins and proteins without known enzymatic activity. These nonenzymatic components can serve as scaffolds or anchors and regulate the efficiency, specificity, and localization of the...

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Библиографические подробности
Главные авторы: Vomastek, Tomas, Schaeffer, Hans-Joerg, Tarcsafalvi, Adel, Smolkin, Mark E., Bissonette, Eric A., Weber, Michael J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC406452/
https://ncbi.nlm.nih.gov/pubmed/15118098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305894101
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