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Mechanism of homophilic adhesion by the neural cell adhesion molecule: Use of multiple domains and flexibility

The extracellular regions of adhesion proteins of the Ig superfamily comprise multiple, tandemly arranged domains. We used directforce measurements to investigate how this modular architecture contributes to the adhesive interactions of the neural cell adhesion molecule (NCAM), a representative of t...

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Autores principales: Johnson, C. P., Fujimoto, I., Perrin-Tricaud, C., Rutishauser, U., Leckband, D.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC406449/
https://ncbi.nlm.nih.gov/pubmed/15118102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307567100
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