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Mechanism of homophilic adhesion by the neural cell adhesion molecule: Use of multiple domains and flexibility

The extracellular regions of adhesion proteins of the Ig superfamily comprise multiple, tandemly arranged domains. We used directforce measurements to investigate how this modular architecture contributes to the adhesive interactions of the neural cell adhesion molecule (NCAM), a representative of t...

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Bibliografiske detaljer
Main Authors: Johnson, C. P., Fujimoto, I., Perrin-Tricaud, C., Rutishauser, U., Leckband, D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC406449/
https://ncbi.nlm.nih.gov/pubmed/15118102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307567100
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