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Heterochromatin on the inactive X chromosome delays replication timing without affecting origin usage

DNA replication origins (ORIs) map close to promoter regions in many organisms, including mammals. However, the relationship between initiation of replication and transcription is not well understood. To address this issue, we have analyzed replication timing and activity of several CpG island-assoc...

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Detalhes bibliográficos
Main Authors: Gómez, María, Brockdorff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC406443/
https://ncbi.nlm.nih.gov/pubmed/15105447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401854101
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