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Heterochromatin on the inactive X chromosome delays replication timing without affecting origin usage

DNA replication origins (ORIs) map close to promoter regions in many organisms, including mammals. However, the relationship between initiation of replication and transcription is not well understood. To address this issue, we have analyzed replication timing and activity of several CpG island-assoc...

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Autori principali: Gómez, María, Brockdorff, Neil
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC406443/
https://ncbi.nlm.nih.gov/pubmed/15105447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401854101
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