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Endosomal H(2)O(2) production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling

Lysophosphatidic acid (LPA) is a growth factor for many cells including prostate and ovarian cancer-derived cell lines. LPA stimulates H(2)O(2) production which is required for growth. However, there are significant gaps in our understanding of the spatial and temporal regulation of H(2)O(2)-depende...

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Autors principals: Klomsiri, Chananat, Rogers, LeAnn C., Soito, Laura, McCauley, Anita K., King, S. Bruce, Nelson, Kimberly J., Poole, Leslie B., Daniel, Larry W.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064372/
https://ncbi.nlm.nih.gov/pubmed/24657741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.03.017
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