Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

Chronic graft-versus-host disease (cGVHD) is a leading cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Having shown that germinal center (GC) formation and immunoglobulin deposition are required for multiorgan system cGVHD and associated bronchiolitis oblit...

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Main Authors: Flynn, Ryan, Du, Jing, Veenstra, Rachelle G., Reichenbach, Dawn K., Panoskaltsis-Mortari, Angela, Taylor, Patricia A., Freeman, Gordon J., Serody, Jonathan S., Murphy, William J., Munn, David H., Sarantopoulos, Stefanie, Luznik, Leo, Maillard, Ivan, Koreth, John, Cutler, Corey, Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Dubovsky, Jason A., Byrd, John C., MacDonald, Kelli P., Hill, Geoff R., Blazar, Bruce R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2014
Fag:
Transplantation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064335/
https://ncbi.nlm.nih.gov/pubmed/24820310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-03-562231
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