Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma

BACKGROUND: The aim of this study was to clarify the role of global hypomethylation of repetitive elements in determining the genetic and clinical features of multiple myeloma (MM). METHODS: We assessed global methylation levels using four repetitive elements (long interspersed nuclear element-1 (LI...

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Main Authors: Aoki, Yuka, Nojima, Masanori, Suzuki, Hiromu, Yasui, Hiroshi, Maruyama, Reo, Yamamoto, Eiichiro, Ashida, Masami, Itagaki, Mitsuhiro, Asaoku, Hideki, Ikeda, Hiroshi, Hayashi, Toshiaki, Imai, Kohzoh, Mori, Mitsuru, Tokino, Takashi, Ishida, Tadao, Toyota, Minoru, Shinomura, Yasuhisa
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064317/
https://ncbi.nlm.nih.gov/pubmed/23259664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm402
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