Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling

BACKGROUND: Glucocorticoids, such as prednisolone, are widely used anti-inflammatory drugs, but therapy is hampered by a broad range of metabolic side effects including skeletal muscle wasting and insulin resistance. Therefore, development of improved synthetic glucocorticoids that display similar e...

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Detalhes bibliográficos
Main Authors: Ellero-Simatos, Sandrine, Szymańska, Ewa, Rullmann, Ton, Dokter, Wim HA, Ramaker, Raymond, Berger, Ruud, van Iersel, Thijs MP, Smilde, Age K, Hankemeier, Thomas, Alkema, Wynand
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064315/
https://ncbi.nlm.nih.gov/pubmed/23199229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm395
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