Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment

BACKGROUND: Translational research typically aims to identify and functionally validate individual, disease-specific genes. However, reaching this aim is complicated by the involvement of thousands of genes in common diseases, and that many of those genes are pleiotropic, that is, shared by several...

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Main Authors: Gustafsson, Mika, Edström, Måns, Gawel, Danuta, Nestor, Colm E, Wang, Hui, Zhang, Huan, Barrenäs, Fredrik, Tojo, James, Kockum, Ingrid, Olsson, Tomas, Serra-Musach, Jordi, Bonifaci, Núria, Pujana, Miguel Angel, Ernerudh, Jan, Benson, Mikael
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064311/
https://ncbi.nlm.nih.gov/pubmed/24571673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm534
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