DNA Methylation Changes Separate Allergic Patients from Healthy Controls and May Reflect Altered CD4(+) T-Cell Population Structure

Altered DNA methylation patterns in CD4(+) T-cells indicate the importance of epigenetic mechanisms in inflammatory diseases. However, the identification of these alterations is complicated by the heterogeneity of most inflammatory diseases. Seasonal allergic rhinitis (SAR) is an optimal disease mod...

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Detalhes bibliográficos
Main Authors: Nestor, Colm E., Barrenäs, Fredrik, Wang, Hui, Lentini, Antonio, Zhang, Huan, Bruhn, Sören, Jörnsten, Rebecka, Langston, Michael A., Rogers, Gary, Gustafsson, Mika, Benson, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879208/
https://ncbi.nlm.nih.gov/pubmed/24391521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004059
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