Serum under-O-glycosylated IgA1 level is not correlated with glomerular IgA deposition based upon heterogeneity in the composition of immune complexes in IgA nephropathy

BACKGROUND: Although serum under-O-glycosylated IgA1 in IgA nephropathy (IgAN) patients may deposit more preferentially in glomeruli than heavily-O-glycosylated IgA1, the relationship between the glomerular IgA deposition level and the O-glycan profiles of serum IgA1 remains obscure. METHODS: Serum...

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Main Authors: Satake, Kenji, Shimizu, Yoshio, Sasaki, Yohei, Yanagawa, Hiroyuki, Suzuki, Hitoshi, Suzuki, Yusuke, Horikoshi, Satoshi, Honda, Shinichiro, Shibuya, Kazuko, Shibuya, Akira, Tomino, Yasuhiko
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064268/
https://ncbi.nlm.nih.gov/pubmed/24928472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-15-89
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