Determination of Severity of Murine IgA Nephropathy by Glomerular Complement Activation by Aberrantly Glycosylated IgA and Immune Complexes

The pathogenic roles of glomerular deposition of components of the complement cascade in IgA nephropathy (IgAN) are not completely clarified. To investigate the pathologic role of complement pathways in IgAN, two IgAN-prone mouse models were examined. Grouped ddY (gddY) mice showed significant high...

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Main Authors: Hashimoto, Azusa, Suzuki, Yusuke, Suzuki, Hitoshi, Ohsawa, Isao, Brown, Rhubell, Hall, Stacy, Tanaka, Yuichi, Novak, Jan, Ohi, Hiroyuki, Tomino, Yasuhiko
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463632/
https://ncbi.nlm.nih.gov/pubmed/22871574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.038
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