Determination of Severity of Murine IgA Nephropathy by Glomerular Complement Activation by Aberrantly Glycosylated IgA and Immune Complexes

The pathogenic roles of glomerular deposition of components of the complement cascade in IgA nephropathy (IgAN) are not completely clarified. To investigate the pathologic role of complement pathways in IgAN, two IgAN-prone mouse models were examined. Grouped ddY (gddY) mice showed significant high...

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Bibliografiska uppgifter
Huvudupphovsmän: Hashimoto, Azusa, Suzuki, Yusuke, Suzuki, Hitoshi, Ohsawa, Isao, Brown, Rhubell, Hall, Stacy, Tanaka, Yuichi, Novak, Jan, Ohi, Hiroyuki, Tomino, Yasuhiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2012
Ämnen:
Regular Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463632/
https://ncbi.nlm.nih.gov/pubmed/22871574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.038
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