Emerging role of the β-catenin-PPARγ axis in the pathogenesis of colorectal cancer

Multiple lines of evidence indicate that Wnt/β-catenin signaling plays a fundamental role in colorectal cancer (CRC) initiation and progression. Recent genome-wide data have confirmed that in CRC this pathway is one of the most frequently modified by genetic or epigenetic alterations affecting almos...

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Main Authors: Sabatino, Lina, Pancione, Massimo, Votino, Carolina, Colangelo, Tommaso, Lupo, Angelo, Novellino, Ettore, Lavecchia, Antonio, Colantuoni, Vittorio
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064060/
https://ncbi.nlm.nih.gov/pubmed/24966585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i23.7137
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