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Dose- and Time-Dependent Epigenetic Changes in the Livers of Fisher 344 Rats Exposed to Furan

The presence of furan in common cooked foods along with evidence from experimental studies that lifetime exposure to furan causes liver tumors in rats and mice has caused concern to regulatory public health agencies worldwide; however, the mechanisms of the furan-induced hepatocarcinogenicity remain...

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Autori principali: de Conti, Aline, Kobets, Tetyana, Escudero-Lourdes, Claudia, Montgomery, Beverly, Tryndyak, Volodymyr, Beland, Frederick Alan, Doerge, Daniel R., Pogribny, Igor Petrovych
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064012/
https://ncbi.nlm.nih.gov/pubmed/24614236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu044
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