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Modeling the Zebrafish Segmentation Clock’s Gene Regulatory Network Constrained by Expression Data Suggests Evolutionary Transitions Between Oscillating and Nonoscillating Transcription

During segmentation of vertebrate embryos, somites form in accordance with a periodic pattern established by the segmentation clock. In the zebrafish (Danio rerio), the segmentation clock includes six hairy/enhancer of split-related (her/hes) genes, five of which oscillate due to negative autofeedba...

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Autors principals: Schwendinger-Schreck, Jamie, Kang, Yuan, Holley, Scott A.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063927/
https://ncbi.nlm.nih.gov/pubmed/24663100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.163642
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