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The Her7 node modulates the network topology of the zebrafish segmentation clock via sequestration of the Hes6 hub

Using in vitro and in vivo assays, we define a network of Her/Hes dimers underlying transcriptional negative feedback within the zebrafish segmentation clock. Some of the dimers do not appear to be DNA-binding, whereas those dimers that do interact with DNA have distinct preferences for cis regulato...

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Autors principals: Trofka, Anna, Schwendinger-Schreck, Jamie, Brend, Tim, Pontius, William, Emonet, Thierry, Holley, Scott A.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274355/
https://ncbi.nlm.nih.gov/pubmed/22278920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.073544
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