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Pax7 Is Necessary and Sufficient for the Myogenic Specification of CD45(+):Sca1(+) Stem Cells from Injured Muscle
CD45(+):Sca1(+) adult stem cells isolated from uninjured muscle do not display any myogenic potential, whereas those isolated from regenerating muscle give rise to myoblasts expressing the paired-box transcription factor Pax7 and the bHLH factors Myf5 and MyoD. By contrast, CD45(+):Sca1(+) isolated...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC406392/ https://ncbi.nlm.nih.gov/pubmed/15138500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020130 |
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