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Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis

We assessed viable Pax7 (−) (/) (−) mice in 129Sv/J background and observed reduced growth and marked muscle wasting together with a complete absence of functional satellite cells. Acute injury resulted in an extreme deficit in muscle regeneration. However, a small number of regenerated myofibers we...

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Detalhes bibliográficos
Main Authors: Kuang, Shihuan, Chargé, Sophie B., Seale, Patrick, Huh, Michael, Rudnicki, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063538/
https://ncbi.nlm.nih.gov/pubmed/16391000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200508001
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