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An Unexpected Link Between Notch Signaling and ROS in Restricting the Differentiation of Hematopoietic Progenitors in Drosophila

A fundamental question in hematopoietic development is how multipotent progenitors achieve precise identities, while the progenitors themselves maintain quiescence. In Drosophila melanogaster larvae, multipotent hematopoietic progenitors support the production of three lineages, exhibit quiescence i...

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Hlavní autoři: Small, Chiyedza, Ramroop, Johnny, Otazo, Maria, Huang, Lawrence H., Saleque, Shireen, Govind, Shubha
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063908/
https://ncbi.nlm.nih.gov/pubmed/24318532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.159210
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