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Sumoylation is tumor-suppressive and confers proliferative quiescence to hematopoietic progenitors in Drosophila melanogaster larvae

How cell-intrinsic regulation of the cell cycle and the extrinsic influence of the niche converge to provide proliferative quiescence, safeguard tissue integrity, and provide avenues to stop stem cells from giving rise to tumors is a major challenge in gene therapy and tissue engineering. We explore...

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Détails bibliographiques
Auteurs principaux: Kalamarz, Marta E., Paddibhatla, Indira, Nadar, Christina, Govind, Shubha
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507282/
https://ncbi.nlm.nih.gov/pubmed/23213407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.2012043
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