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Mre11 Assembles Linear DNA Fragments into DNA Damage Signaling Complexes
Mre11/Rad50/Nbs1 complex (MRN) is essential to suppress the generation of double-strand breaks (DSBs) during DNA replication. MRN also plays a role in the response to DSBs created by DNA damage. Hypomorphic mutations in Mre11 (which causes an ataxia-telangiectasia-like disease [ATLD]) and mutations...
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| Publicat a: | PLoS Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
PLOS
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC406388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15138496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1371/journal.pbio.0020110 |
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