Cell Cycle Modulation by Marek’s Disease Virus: The Tegument Protein VP22 Triggers S-Phase Arrest and DNA Damage in Proliferating Cells

Marek’s disease is one of the most common viral diseases of poultry affecting chicken flocks worldwide. The disease is caused by an alphaherpesvirus, the Marek’s disease virus (MDV), and is characterized by the rapid onset of multifocal aggressive T-cell lymphoma in the chicken host. Although severa...

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Detalhes bibliográficos
Main Authors: Trapp-Fragnet, Laëtitia, Bencherit, Djihad, Chabanne-Vautherot, Danièle, Le Vern, Yves, Remy, Sylvie, Boutet-Robinet, Elisa, Mirey, Gladys, Vautherot, Jean-François, Denesvre, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063868/
https://ncbi.nlm.nih.gov/pubmed/24945933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100004
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