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Fluorescent tagging of VP22 in N-terminus reveals that VP22 favors Marek’s disease virus (MDV) virulence in chickens and allows morphogenesis study in MD tumor cells

Marek’s disease virus (MDV) is an alpha-herpesvirus causing Marek’s disease in chickens, mostly associated with T-cell lymphoma. VP22 is a tegument protein abundantly expressed in cells during the lytic cycle, which is essential for MDV spread in culture. Our aim was to generate a pathogenic MDV exp...

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Detalhes bibliográficos
Main Authors: Rémy, Sylvie, Blondeau, Caroline, Vern, Yves Le, Lemesle, Monique, Vautherot, Jean-François, Denesvre, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899609/
https://ncbi.nlm.nih.gov/pubmed/24359464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9716-44-125
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