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Vaccination against Clostridium difficile using toxin fragments: Observations and analysis in animal models

Clostridium difficile is a major cause of antibiotic associated diarrhea. Recently, we have shown that effective protection can be mediated in hamsters through the inclusion of specific recombinant fragments from toxin A and B in a systemically delivered vaccine. Interestingly while neutralizing ant...

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Autores principales: Spencer, Janice, Leuzzi, Rosanna, Buckley, Anthony, Irvine, June, Candlish, Denise, Scarselli, Maria, Douce, Gillian R
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063849/
https://ncbi.nlm.nih.gov/pubmed/24637800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.27712
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