Protective Efficacy Induced by Recombinant Clostridium difficile Toxin Fragments

Clostridium difficile is a spore-forming bacterium that can reside in animals and humans. C. difficile infection causes a variety of clinical symptoms, ranging from diarrhea to fulminant colitis. Disease is mediated by TcdA and TcdB, two large enterotoxins released by C. difficile during colonizatio...

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Bibliografiske detaljer
Main Authors: Leuzzi, Rosanna, Spencer, Janice, Buckley, Anthony, Brettoni, Cecilia, Martinelli, Manuele, Tulli, Lorenza, Marchi, Sara, Luzzi, Enrico, Irvine, June, Candlish, Denise, Veggi, Daniele, Pansegrau, Werner, Fiaschi, Luigi, Savino, Silvana, Swennen, Erwin, Cakici, Osman, Oviedo-Orta, Ernesto, Giraldi, Monica, Baudner, Barbara, D'Urzo, Nunzia, Maione, Domenico, Soriani, Marco, Rappuoli, Rino, Pizza, Mariagrazia, Douce, Gillian R., Scarselli, Maria
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Bacterial Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719595/
https://ncbi.nlm.nih.gov/pubmed/23716610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01341-12
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