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A global profile of gene promoter methylation in treatment-naïve urothelial cancer
The epigenetic alteration of aberrant hypermethylation in the promoter CpG island of a gene is associated with repression of transcription. In neoplastic cells, aberrant hypermethylation is well described as a mechanism of allele inactivation of particular genes with a tumor suppressor function. To...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4063835/ https://ncbi.nlm.nih.gov/pubmed/24521710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.28078 |
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