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Epipolymorphisms within lipoprotein genes contribute independently to plasma lipid levels in familial hypercholesterolemia

Gene polymorphisms associated so far with plasma lipid concentrations explain only a fraction of their heritability, which can reach up to 60%. Recent studies suggest that epigenetic modifications (DNA methylation) could contribute to explain part of this missing heritability. We therefore assessed...

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Detalhes bibliográficos
Main Authors: Guay, Simon-Pierre, Brisson, Diane, Lamarche, Benoit, Gaudet, Daniel, Bouchard, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063831/
https://ncbi.nlm.nih.gov/pubmed/24504152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27981
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