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The elevation of plasma concentrations of apoB-48-containing lipoproteins in familial hypercholesterolemia is independent of PCSK9 levels

BACKGROUND: Previous studies have reported high plasma concentrations of both intestinal apolipoprotein (apo) B-48-containing lipoproteins and PCSK9 in subjects with familial hypercholesterolemia (FH). However, the extent to which LDL receptor deficiency and PCSK9 levels influence plasma apoB-48 con...

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Drouin-Chartier, Jean-Philippe, Hogue, Jean-Charles, Tremblay, André J., Bergeron, Jean, Lamarche, Benoît, Couture, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472856/
https://ncbi.nlm.nih.gov/pubmed/28619117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-017-0502-x
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