STAT3 Modulation to Enhance Motor Neuron Differentiation in Human Neural Stem Cells

Spinal cord injury or amyotrophic lateral sclerosis damages spinal motor neurons and forms a glial scar, which prevents neural regeneration. Signal transducer and activator of transcription 3 (STAT3) plays a critical role in astrogliogenesis and scar formation, and thus a fine modulation of STAT3 si...

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Detalhes bibliográficos
Main Authors: Natarajan, Rajalaxmi, Singal, Vinamrata, Benes, Richard, Gao, Junling, Chan, Hoi, Chen, Haijun, Yu, Yongjia, Zhou, Jia, Wu, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063761/
https://ncbi.nlm.nih.gov/pubmed/24945434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100405
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