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Gd(3+) and Calcium Sensitive, Sodium Leak Currents Are Features of Weak Membrane-Glass Seals in Patch Clamp Recordings

The properties of leaky patch currents in whole cell recording of HEK-293T cells were examined as a means to separate these control currents from expressed sodium and calcium leak channel currents from snail NALCN leak channels possessing both sodium (EKEE) and calcium (EEEE) selectivity filters. Le...

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Main Authors: Boone, Adrienne N., Senatore, Adriano, Chemin, Jean, Monteil, Arnaud, Spafford, J. David
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063719/
https://ncbi.nlm.nih.gov/pubmed/24945283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098808
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