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Hypoxia regulates Toll-like receptor-9 expression and invasive function in human brain cancer cells in vitro

Toll-like receptor-9 (TLR9) is a cellular DNA sensor of the innate immune system. TLR9 is widely expressed in a number of tumors, including brain cancer; however, little is known regarding its regulation and involvement in cancer pathophysiology. The present study demonstrated that hypoxia upregulat...

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Detalhes bibliográficos
Main Authors: SANDHOLM, JOUKO, TUOMELA, JOHANNA, KAUPPILA, JOONAS H., HARRIS, KEVIN W., GRAVES, DAVID, SELANDER, KATRI S.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063648/
https://ncbi.nlm.nih.gov/pubmed/24959259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2095
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