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Preventive effects of the angiotensin-converting enzyme inhibitor, captopril, on the development of azoxymethane-induced colonic preneoplastic lesions in diabetic and hypertensive rats

Metabolic syndrome (Mets), including diabetes and hypertension, increases the risk of colorectal cancer via the induction of chronic inflammation, acceleration of oxidative stress, and activation of the renin-angiotensin system. The present study examined the possible inhibitory effects of captopril...

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Detalhes bibliográficos
Main Authors: KOCHI, TAKAHIRO, SHIMIZU, MASAHITO, OHNO, TOMOHIKO, BABA, ATSUSHI, SUMI, TAKAFUMI, KUBOTA, MASAYA, SHIRAKAMI, YOHEI, TSURUMI, HISASHI, TANAKA, TAKUJI, MORIWAKI, HISATAKA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063600/
https://ncbi.nlm.nih.gov/pubmed/24959250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2136
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