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Preventive effects of the angiotensin-converting enzyme inhibitor, captopril, on the development of azoxymethane-induced colonic preneoplastic lesions in diabetic and hypertensive rats

Metabolic syndrome (Mets), including diabetes and hypertension, increases the risk of colorectal cancer via the induction of chronic inflammation, acceleration of oxidative stress, and activation of the renin-angiotensin system. The present study examined the possible inhibitory effects of captopril...

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Bibliografske podrobnosti
Main Authors: KOCHI, TAKAHIRO, SHIMIZU, MASAHITO, OHNO, TOMOHIKO, BABA, ATSUSHI, SUMI, TAKAFUMI, KUBOTA, MASAYA, SHIRAKAMI, YOHEI, TSURUMI, HISASHI, TANAKA, TAKUJI, MORIWAKI, HISATAKA
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063600/
https://ncbi.nlm.nih.gov/pubmed/24959250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2136
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