Combination of dasatinib and gemcitabine reduces the ALDH1A1 expression and the proliferation of gemcitabine-resistant pancreatic cancer MIA PaCa-2 cells

Gemcitabine-based chemotherapy is the standard for treatment of pancreatic cancer; however, intrinsic and acquired resistance to gemcitabine commonly occurs. Aldehyde dehydrogenase 1A1 (ALDH1A1), one of the characteristic features of tumor-initiating and/or cancer stem cell (CSC) properties, is impo...

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Hlavní autoři: DUONG, HONG-QUAN, YI, YONG WEON, KANG, HYO JIN, BAE, INSOO, JANG, YOUNG-JOO, KWAK, SAHNG-JUNE, SEONG, YEON-SUN
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2014
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063532/
https://ncbi.nlm.nih.gov/pubmed/24676703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2357
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