Nicotinic Acid Activates the Capsaicin Receptor TRPV1 – A Potential Mechanism for Cutaneous Flushing

OBJECTIVE: Nicotinic acid (a.k.a. niacin or vitamin B3), widely used to treat dyslipidemias, represents an effective and safe means to reduce the risk of mortality from cardiovascular disease. Nonetheless, a substantial fraction of patients discontinue treatment due to a strong side effect of cutane...

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Main Authors: Ma, Linlin, Lee, Bo Hyun, Mao, Rongrong, Cai, Anping, Jia, Yunfang, Clifton, Heather, Schaefer, Saul, Xu, Lin, Zheng, Jie
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063526/
https://ncbi.nlm.nih.gov/pubmed/24675661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.303346
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