Identifying the Elusive Sites of Tyrosyl Radicals in Cytochrome c Peroxidase: Implications for Oxidation of Substrates Bound at a Site Remote from the Heme

[Image: see text] The location of the Trp radical and the catalytic function of the [Fe(IV)=O Trp(191)(•+)] intermediate in cytochrome c peroxidase (CcP) are well-established; however, the unambiguous identification of the site(s) for the formation of tyrosyl radical(s) and their possible biological...

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Auteurs principaux: Miner, Kyle D., Pfister, Thomas D., Hosseinzadeh, Parisa, Karaduman, Nadime, Donald, Lynda J., Loewen, Peter C., Lu, Yi, Ivancich, Anabella
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2014
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063442/
https://ncbi.nlm.nih.gov/pubmed/24901481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500353p
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