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Parahydrogen Induced Polarization of 1-(13)C-Phospholactate-d(2) for Biomedical Imaging with >30,000,000-fold NMR Signal Enhancement in Water

[Image: see text] The synthetic protocol for preparation of 1-(13)C-phosphoenolpyruvate-d(2), precursor for parahydrogen-induced polarization (PHIP) of 1-(13)C-phospholactate-d(2), is reported. (13)C nuclear spin polarization of 1-(13)C-phospholactate-d(2) was increased by >30,000,000-fold (5.75...

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Bibliographische Detailangaben
Hauptverfasser: Shchepin, Roman V., Coffey, Aaron M., Waddell, Kevin W., Chekmenev, Eduard Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063326/
https://ncbi.nlm.nih.gov/pubmed/24738968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac500952z
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