Interleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment

BACKGROUND: Interleukin-17 (IL-17) has been demonstrated to promote formation and growth of hormone-naïve prostate adenocarcinoma in mice. IL-17’s role in development of castration-resistant prostate cancer is unknown. In the present study, we investigated IL-17’s role in castration-resistant prosta...

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Autori principali: Zhang, Qiuyang, Liu, Sen, Zhang, Qingsong, Xiong, Zhenggang, Wang, Alun R., Myers, Leann, Melamed, Jonathan, Tang, Wendell W., You, Zongbing
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063299/
https://ncbi.nlm.nih.gov/pubmed/24691769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22805
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