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Iron-induced parafibrin formation in tumors fosters immune evasion

Although efficacious in vitro, it is well known that adoptive immunotherapeutic modalities lose their potency when applied in vivo. Furthermore, malignant cell exposure to blood platelets attenuates the anticancer activity of natural killer (NK) cells. We argue that upon contact with redox iron, fib...

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Detalles Bibliográficos
Autor Principal: Lipinski, Boguslaw
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063136/
https://ncbi.nlm.nih.gov/pubmed/25050219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28539
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