Hyperinsulinemia is Associated with Increased Soluble Insulin Receptors Release from Hepatocytes

It has been generally assumed that insulin circulates freely in blood. However it can also interact with plasma proteins. Insulin receptors are located in the membrane of target cells and consist of an alpha and beta subunits with a tyrosine kinase cytoplasmic domain. The ectodomain, called soluble...

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Hlavní autoři: Hiriart, Marcia, Sanchez-Soto, Carmen, Diaz-Garcia, Carlos Manlio, Castanares, Diana T., Avitia, Morena, Velasco, Myrian, Mas-Oliva, Jaime, Macias-Silva, Marina, González-Villalpando, Clicerio, Delgado-Coello, Blanca, Sosa-Garrocho, Marcela, Vidaltamayo, Román, Fuentes-Silva, Deyanira
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062980/
https://ncbi.nlm.nih.gov/pubmed/24995000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00095
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