Hyperinsulinemia is Associated with Increased Soluble Insulin Receptors Release from Hepatocytes

It has been generally assumed that insulin circulates freely in blood. However it can also interact with plasma proteins. Insulin receptors are located in the membrane of target cells and consist of an alpha and beta subunits with a tyrosine kinase cytoplasmic domain. The ectodomain, called soluble...

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Bibliografiska uppgifter
Huvudupphovsmän: Hiriart, Marcia, Sanchez-Soto, Carmen, Diaz-Garcia, Carlos Manlio, Castanares, Diana T., Avitia, Morena, Velasco, Myrian, Mas-Oliva, Jaime, Macias-Silva, Marina, González-Villalpando, Clicerio, Delgado-Coello, Blanca, Sosa-Garrocho, Marcela, Vidaltamayo, Román, Fuentes-Silva, Deyanira
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2014
Ämnen:
Endocrinology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062980/
https://ncbi.nlm.nih.gov/pubmed/24995000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00095
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