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Growth of v-src-Transformed Cells in Serum-Free Medium Through the Induction of Growth Factors

The v-src oncogene is one of only two oncogenes capable of transforming mouse embryo fibroblasts (MEFs) lacking the IGF-IR gene (R-cells). R-/v-src cells grow robustly in the absence of serum, suggesting the hypothesis that they may produce one or more growth factors that would sustain their ability...

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Hlavní autoři: DEANGELIS, TIZIANA, QUONG, ANDREW, MORRIONE, ANDREA, BASERGA, RENATO
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062974/
https://ncbi.nlm.nih.gov/pubmed/23254450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24303
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