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Androgen Receptor Activation in Castration-Recurrent Prostate Cancer: The Role of Src-Family and Ack1 Tyrosine Kinases

There is growing appreciation that castration-recurrent prostate cancer (CR-CaP) is driven by the continued expression of androgen receptor (AR). AR activation in CR-CaP through various mechanisms, including AR overexpression, expression of AR splice variants or mutants, increased expression of co-r...

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Bibliographic Details
Main Author: Gelman, Irwin H.
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062955/
https://ncbi.nlm.nih.gov/pubmed/24948875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.8264
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